Collectively, results of those studies are consistent with the demonstrated clastogenicity (chromosome-breaking ability) of cigarette smoke and condensate and cigarette smoke in experimental systems and in humans. Several of these studies (IARC 2004) indicated that reactive oxygen or nitrogen species will be the major reason for the breaks in DNA strands. The increased mutagenicity of… Continue reading The Flavour Issue: How Minimize Tobacco Filler Shapes Your Smoke